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前列腺素已经查明也存在于眼组织中,据Ambache氏(1957)从兔眼虹膜组织中提取一种能使瞳孔括约肌收缩的物质,称为虹膜素,以后经证实此种物质,就是PGE_2及PGF_(2α)所构成。目前已了解虹膜及一些组织具有合成PG的功能。如眼部机械性创伤、前房穿刺、激光照射、炎症及化学性刺激等均能引起房水中PG含量的显著升高,而引起睫状充血、虹膜充血及瞳孔缩小等改变。 PG在眼科领域中,已知有PGE_1、PGE_2及PGF_(2α)三种,它在眼内的生理及病理生理的作用简介如下: 一、PG与血—房水屏障:实验证明内、外源性PG都能破坏血—房水屏障的作用,如眼外伤引起眼内PG的合成和释放,它具有促
Prostaglandin has also been identified in ocular tissues. According to Ambache (1957), a substance that can shrink the pupil sphincter, called iris, is extracted from the iris of the rabbit eye and later proved to be PGE 2 and PGF_ (2α). Iris and some organizations have now been known to have the function of synthetic PG. Such as ocular mechanical trauma, anterior chamber puncture, laser irradiation, inflammation and chemical stimulation can cause a significant increase in aqueous humor PG content, causing ciliary congestion, iris congestion and miosis and other changes. PG In the field of ophthalmology, there are three known PGE_1, PGE_2 and PGF_ (2α), its physiological and pathophysiological effects in the eye are as follows: First, PG and blood - atrial water barrier: experimental evidence of exogenous Sex PG can damage the blood - the role of aqueous humor barrier, such as ocular trauma caused by the synthesis and release of intraocular PG, it has a promotion