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目的分析与研究他汀类与心血管药物配伍的安全性。方法分析他汀类和肾素及血管紧张素的转化酶抑制剂、钙拮抗剂、洋地黄类药物、抗心律失常类药物及其他降血脂类药物的配伍情况,并对其安全性进行总结。结果他汀类与肾素及血管紧张素的转化酶抑制剂、钙拮抗剂、洋地黄类药物及其他降血脂类药物配伍的安全性较好,但和抗心律失常类药物配伍需慎重。结论要重视他汀类和心血管类药物的配伍使用,如有需要可在剂量上加以调整,还需注意使用药物疗效的相互影响。
Objective To analyze and study the safety of compatibility of statins and cardiovascular drugs. Methods The compatibility of statins, renin, angiotensin converting enzyme inhibitors, calcium antagonists, digitalis drugs, antiarrhythmic drugs and other antihyperlipidemic drugs was analyzed and their safety was summarized. Results statins and renin and angiotensin converting enzyme inhibitors, calcium antagonists, digitalis and other anti-lipid drugs compatibility is better, but compatibility with anti-arrhythmic drugs need to be cautious. Conclusions It is important to pay attention to the compatibility of statins and cardiovascular drugs, adjust dosage if necessary, and pay attention to the interaction between the effects of drugs.