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内脏和全身小动脉扩张在肝硬化腹水形成中起重要作用。奥曲肽可使内脏血管收缩,但对全身血液动力学和肾功能的影响尚有争议。本研究目的旨在评估皮下给予奥曲肽对肝硬化腹水病人的全身血液动力学、内源性血管活性系统和肾功能的影响。
Visceral and systemic arteriolar dilatation play an important role in the formation of cirrhotic ascites. Octreotide can visceral vasoconstriction, but the impact on systemic hemodynamics and renal function is still controversial. The purpose of this study was to evaluate the effects of subcutaneous octreotide administration on systemic hemodynamics, endogenous vasoactive systems and renal function in cirrhotic patients with ascites.