用免疫学方法预防龋齿通常依据以下3种假设.首先,龋齿是一种传染病;第二,致龋菌在定居、生长或致病过程中易于遭受免疫学攻击;第三,宿主特异性免疫防御系统产生的物质在易感部位逗留时间足以阻止牙釉质脱钙毁坏.本文讨论了这些假设的证据,并且对口服免疫接种诱导抗龋齿免疫力问题进行了研究. First, caries is an infectious disease; second, cariogenic bacteria are susceptible to immunological attack during colonization, growth or pathogenicity; third, host-specific immunity The substance produced by the defense system stays in the susceptible part for a time sufficient to prevent the decalcification of enamel from decaying.This paper discusses the evidence of these hypotheses and examines the anti-cariogenic immunity induced by oral immunization.