目的研究柳蒿Artemisia selengensis全草的化学成分。方法采用硅胶柱色谱、高效液相色谱等方法进行分离纯化,通过理化性质及核磁共振谱、质谱等光谱数据分析鉴定结构。结果从柳蒿全草甲醇提取液醋酸乙酯萃取物中分离得到1个双倍半萜类化合物。结论该双倍半萜为未见报道的新化合物,命名为柳蒿素A。 Objective To study the chemical constituents of Artemisia selengensis. Methods The compounds were isolated and purified by silica gel column chromatography and high performance liquid chromatography (HPLC). The structures were elucidated by physicochemical properties, NMR and MS spectra. Results A half sesquiterpenoid compound was isolated from the ethyl acetate extract of the whole plant methanol extract of Artemisia selengensis. Conclusions The sesquiterpene is a new compound which has not been reported and named as artemisinin A.