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目的:分析医院脊柱外科围手术期患者抗菌药物的使用情况,为加强临床抗菌药物合理使用和规范管理提供参考。方法:采用回顾性方法,从抗菌药物品种、用法与用量及药物经济学等角度,分析医院2013年7月—12月间脊柱外科Ⅰ类切口手术患者393例围手术期抗菌药物的使用情况。结果:脊柱外科手术患者中,未使用抗菌药物者为87例(占22.14%),使用抗菌药物者为310例(占78.88%),其中单一用药者为302例(占76.84%),联合用药者为4例(占1.02%);抗菌药物给药时机合理率为86.01%,抗菌药物使用疗程合理率为73.79%。结论:医院脊柱外科围手术期患者抗菌药物的使用基本合理,但存在无适应证用药、给药时机错误、用药疗程过长等问题,故应采取有效地干预措施,促进临床合理用药。
Objective: To analyze the use of antimicrobial agents in patients undergoing perioperative surgery for spine surgery in hospitals and provide reference for rational use and standard management of clinical antimicrobial agents. Methods: A retrospective study was conducted to analyze the perioperative use of antimicrobial agents in 393 patients with type Ⅰ incision surgery from July 2013 to December 2013 in hospitals from the aspects of antimicrobial varieties, usage and dosage, and pharmacoeconomics. RESULTS: Among spine surgery patients, 87 (22.14%) did not use antimicrobial agents, 310 (78.88%) used antimicrobial agents, and 302 (76.84%) were single agents, 4 cases (accounting for 1.02%); the timing of administration of antibacterials was 86.01%, and the rational use of antibacterials was 73.79%. Conclusion: The use of antimicrobial agents in patients undergoing perioperative surgical treatment of spinal surgery is basically reasonable. However, there are some problems such as no indications, incorrect timing of drug delivery and long course of treatment. Therefore, effective interventions should be taken to promote rational drug use in clinical practice.