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患者,男,46岁,江苏省无锡市焦化厂焦炉车间炼焦工,专业工龄17年。患者于2005年、2007年、2009年连续3次职业健康检查中发现血常规异常。2010年9月14日,患者因“发现血小板减少五年,全身皮肤出现瘀斑两天”就诊无锡市人民医院,查血常规:白细胞4.5×10~9/L,红细胞计数3.2×10~9/L,血红蛋白120g/L,血小板18×10~9/L,收治入院。既往史:患者2005年以前无健康体检资料,自感身体健康,无特殊服药史,无放射线接触史和家族血液病史。临床诊断:①MOS-RCUD-RT(难治性血小板减少症,2008年新WHO分型);②Ⅱ型糖尿病;③急性支气管炎。患者经药物治疗后,病情缓和于2010年10月16日出院。探讨重度苯中毒致骨髓增生异常综合征,并提醒注意预防和避免其发生。
Patients, male, 46 years old, coking plant in Wuxi City, Jiangsu Province, coke oven coking workers, professional seniority of 17 years. Patients in 2005, 2007, 2009, three consecutive occupational health examination found abnormal blood tests. On September 14, 2010, Wuxi People’s Hospital visited Wuxi City People’s Hospital for “five-year thrombocytopenia reduction and two-day ecchymosis on whole body skin.” Blood test: white blood cells 4.5 × 10 ~ 9 / L, erythrocyte count 3.2 × 10 ~ 9 / L, hemoglobin 120g / L, platelets 18 × 10 ~ 9 / L, admitted to hospital. Past history: Prior to 2005, patients had no physical examination data, felt physically healthy, had no history of special medication, had no history of radiation exposure, and had a history of familial blood disease. Clinical diagnosis: ①MOS-RCUD-RT (refractory thrombocytopenia, the new WHO classification in 2008); ② type Ⅱ diabetes; ③ acute bronchitis. Patients after drug treatment, the condition was relieved on October 16, 2010 discharged. To explore severe benzene poisoning caused by myelodysplastic syndrome, and to remind the attention to prevention and avoid its occurrence.