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为探讨活血祛瘀生新中药制剂“安宫饮”(由当归、川芎、益母草、桃仁、枳壳、七叶一枝花、蒲黄等8味中药组成)的临床疗效及临床使用的安全性,通过对7周内早孕者给予口服米非司酮和米索前列醇进行药物流产后,治疗组加服安宫饮,对照组不加用其他治疗手段,观察其出血量及出血时间,并进行统计学分析。结果:治疗组出血量轻中度百分比为78.69%,高于对照组(52.73%)(P<0.01);治疗组平均出血时间为(13.5±6.08)d,比对照组(17.8±9.37)d低(P<0.01);治疗组出血天数在14d内者所占百分比为72.13%,高于对照组(50.91%)(P<0.05)。表明安宫饮能减少药物流产后出血量,缩短出血时间,促进恶露早日排净,对药物流产后阴道出血有确切疗效。本研究未发现安宫饮任何毒副作用,说明该药在临床应用是安全的。
In order to explore the clinical curative effect and safety of clinical application of “An Gong Yin” (a traditional Chinese medicine composed of Chinese angelica root, Chuanxiong, Motherwort, Peach kernel, Citrus aurantium, Amaryllidaceae, Puhuang, etc.) After 7 weeks of early pregnancy were given oral mifepristone and misoprostol for medical abortion, the treatment group plus An Gong drink, the control group without additional treatment, to observe the amount of bleeding and bleeding time, and Statistical analysis. Results: The mild to moderate bleeding rate in the treatment group was 78.69%, which was higher than that in the control group (52.73%) (P <0.01). The average bleeding time in the treatment group was (13.5 ± 6.08) days (17.8 ± 9.37) d (P <0.01). The percentage of hemorrhage days in the treatment group within 14 days was 72.13%, which was higher than that in the control group (50.91%) (P <0.05). That An Gong drink can reduce the amount of bleeding after medical abortion, shorten the bleeding time and promote an early row of diarrhea net, vaginal bleeding after medical abortion have the exact effect. This study did not find Anyong drink any side effects, indicating that the drug is safe in clinical application.