综述了胰岛素经眼给药的全身吸收,吸收促进剂对胰岛素经眼吸收的作用,增粘剂在胰岛素滴眼剂中的应用及胰岛素经眼吸收的药代动力学等方面的研究近况。还就其临床应用的可行性作了概述,并探讨了胰岛素经眼给药研究中尚待解决的问题。 The recent progress in the systemic absorption of insulin by ocular administration, the effect of absorption enhancers on the absorption of insulin by the eye, the application of viscosifiers in insulin eye drops, and the pharmacokinetics of insulin by eye are reviewed. It also made an overview of the feasibility of its clinical application, and explored the issues that remain to be solved in the study of insulin administration.