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目的 探讨尿微量白蛋白(mALB)在产后急性肾功能损伤中的诊断价值.方法 选取2014年1月-2016年12月在该院妇产科分娩的孕产妇120例作为研究对象,将其中出现产后急性肾功能损伤的40例孕产妇作为观察组,将另外80例未出现产后急性肾功能损伤的80例孕产妇作为对照组.比较两组孕产妇分娩前后mALB、外周血肌酐(Cr)、尿素氮(BUN)、外周平均动脉压(MAP)、肾小球滤过率(GFR)等生化指标的差异.结果 观察组孕产妇平均年龄高于对照组,差异有统计学意义(P＜0.05);观察组孕产妇产后的MAP、Cr、BUN、GFR和mALB指标与对照组比较,差异均有统计学意义(均P＜0.05);Logistic分析产后急性肾损伤的独立危险因素有Cr、mALB和mALB/GFR (P＜0.05);Cr、mALB及mALB/GFR的ROC曲线下面积分别为0.61、0.81、0.72,mALB的ROC曲线下面积与Cr和mALB/GFR比较,差异均有统计学意义(均P＜0.05).结论 mALB作为一种无创检测指标,对产后急性肾功能损伤的诊断具有较高的临床应用价值.后期需对其敏感性和具体机制等进一步研究分析.“,”Objective To explore the diagnostic value of urine microalbumin (mALB) in postpartum acute renal injury.Methods From January 2014 to December 2016,120 pregnant women giving birth to their babies in Department of Gynecology and Obstetrics in Affiliated Tongji Hospital of Tongji University were selected and divided into observation group (40 cases with postpartum acute renal injury) and control group (80 cases without postpartum acute renal injury).mALB,creatinine (Cr) and urea nitrogen (BUN) in peripheral blood,mean arterial pressure (MAP),and glomerular filtration rate (GFR) before and after delivery in the two groups were compared.Results The average age of pregnant women in observation group was statistically significantly higher than that in control group (P＜0.05).There were statistically significant differences in MAP,Cr,BUN,GFR,and mALB after delivery between observation group and control group (P＜0.05).Logistic analysis showed that the independent risk factors of postpartum acute renal injury included Cr,mALB,and mALB/GFR (P＜0.05).The areas under ROC curves of Cr,mALB,and mALB/GFR were 0.61,0.81,and O.72,respectively.There were statistically significant differences in the area under ROC curve between mALB and Cr,mALB/GFR (P＜0.05).Conclusion As a non-invasive detection index,the clinical application value of mALB in diagnosis of postpartum acute renal injury is high.The sensitivity and specific mechanism should be further studied and analyzed.