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白细胞介素10是由多种细胞分泌的多功能细胞因子,能抑制T细胞、巨噬细胞的激活和多种炎症因子、生长因子的合成,是一种理想的抗炎物质。动脉粥样硬化和脑血管病是严重危害人类健康的多发病,且都与慢性炎症密切相关,血管介入术是目前治疗动脉粥样硬化最有效的方法,据研究表明各种介入术后再狭窄率可达25%～50%。文章就白细胞介素10与动脉粥样硬化、介入后再狭窄及脑血管病的关系做一综述。
Interleukin 10 is a multifunctional cytokine secreted by many kinds of cells, which can inhibit the activation of T cells and macrophages and synthesis of various inflammatory and growth factors. It is an ideal anti-inflammatory substance. Atherosclerosis and cerebrovascular disease are serious diseases that endanger human health and are closely related to chronic inflammation. Vascular intervention is the most effective method for the treatment of atherosclerosis. Studies have shown that all kinds of restenosis after interventional surgery The rate of up to 25% to 50%. The article reviews the relationship between interleukin 10 and atherosclerosis, post-interventional restenosis and cerebrovascular disease.