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研究了探针式光纤探头的有效检测深度。采用扩散方程描述光在强散射生物组织中的传播规律,运用纽曼边界条件,使用灵敏度矩阵对有效检测深度进行了研究。灵敏度矩阵和光源与检测器的空间位置分布密切相关。光源与检测器对的灵敏度矩阵定义为:光源位置和检测器位置分别作为光源的光场分布的乘积。设计了6组针对不同参数的模型,参数主要包括光源、检测器光纤芯径、光源、检测器光纤中心距、光纤探头所处的深度、生物组织的吸收系数和散射系数。对探针式光纤探头在各组模型中的有效探测深度进行了仿真,重点研究了六种参数对检测深度的影响。所得结论可以推广到分析光纤检测器的空间分辨率和多光纤检测器的研究中。
The effective detection depth of the probe fiber probe was studied. Diffusion equation is used to describe the propagation of light in strongly scattering biological tissues. Newman boundary conditions are used to study the effective detection depth using the sensitivity matrix. The sensitivity matrix and the spatial distribution of the light source and detector are closely related. The sensitivity matrix of light source and detector pairs is defined as the product of the light field distribution of the light source and the detector position, respectively. Six sets of models are designed for different parameters. The parameters mainly include the light source, the diameter of the detector fiber core, the light source, the center distance of the detector fiber, the depth of the fiber probe, the absorption coefficient and the scattering coefficient of the biological tissue. The effective probing depth of the probe optical fiber probe in each model is simulated, and the influence of six parameters on the depth of detection is studied emphatically. The conclusions can be generalized to the analysis of the spatial resolution of fiber optic detectors and multi-fiber detectors.