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目的:探讨硝酸咪康唑栓联合曲安奈德益康唑乳膏和制霉菌素片治疗外阴阴道假丝酵母菌病(VVC)的临床疗效。方法:应用随机数字表法将2016年1月至2017年1月惠州市第六人民医院妇科收治的88例VVC患者分为治疗组和对照组,每组44例,治疗组予以硝酸咪康唑栓联合曲安奈德益康唑乳膏治疗,对照组予制霉素片治疗,比较两组患者临床疗效总有效率和复发率。结果:治疗组总有效率为95.45%,与对照组治疗总有效率70.45%比较,差异具有统计学意义(P<0.05);治疗组复发率为6.82%,与对照组治疗复发率29.55%比较,差异具有统计学意义(P<0.05)。结论:硝酸咪康唑栓联合曲安奈德益康唑乳膏治疗VVC疗效显著,复发率低,是目前治疗VVC的有效治疗方案,还可预防远期复发。
Objective: To investigate the clinical efficacy of miconazole nitrate suppository combined with triamcinolone acetonide cream and nystatin tablet in the treatment of vulvovaginal candidiasis (VVC). Methods: A total of 88 patients with VVC received gynecology from January 2016 to January 2017 in Huizhou City were divided into treatment group and control group, with 44 cases in each group. The patients in treatment group were treated with miconazole nitrate suppository Triamcinolone acetonide cream treatment, the control group received neomycin tablets treatment, the clinical efficacy of the two groups were compared the total effective rate and recurrence rate. Results: The total effective rate of the treatment group was 95.45%, which was significantly higher than that of the control group (70.45%) (P <0.05). The recurrence rate was 6.82% in the treatment group and 29.55% in the control group , The difference was statistically significant (P <0.05). Conclusion: The combination of miconazole nitrate suppository and triamcinolone acetonide cream for the treatment of VVC has significant curative effect and low recurrence rate. It is an effective treatment for VVC and can prevent long-term recurrence.