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一般认为慢性HBsAg携带者伴或不伴肝功能异常都是发生肝细胞癌(HCC)高危者.为探讨慢性乙型肝炎与HCC的关系,作者用血清AFP定量测定和实时超声波两种方法对临床病理学证实的432例慢性乙型肝炎患者发生HCC的情况作了前瞻性研究.材料和方法:7年中观察432例,患者年龄为15-69岁,平均31岁;127例(29.4%)大于35岁,其中女性53例(12.3%).对照组:105例HBsAg阴性慢性肝炎患者年龄22～70岁,平均43.6岁;35岁以上者占73.3%,女性占34.3%.随访6～85个月(中位数23,平均26.9±16.8)随访中如AFP或超声波或两者都提示HCC时,作选择性肝动脉造影,必要时在超声波引导
Generally believed that chronic HBsAg carriers with or without liver dysfunction are the occurrence of high-risk patients with hepatocellular carcinoma (HCC) .To explore the relationship between chronic hepatitis B and HCC, the author of serum AFP quantitative determination and real-time ultrasonic two methods of clinical Pathological confirmed the occurrence of 432 cases of chronic hepatitis B HCC patients were prospectively studied.Materials and methods: 432 cases were observed in 7 years, the patients aged 15-69 years, mean 31 years; 127 cases (29.4%) In the control group, 105 patients with HBsAg-negative chronic hepatitis aged from 22 to 70 years (mean 43.6 years), 73.3% over 35 and 34.3% women followed up from 6 to 85 Months (median 23, mean 26.9 ± 16.8) at follow-up such as AFP or ultrasound or both prompted HCC for selective hepatic arteriography and, if necessary, ultrasound guidance