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目的观察西甲硅油在胶囊内镜检查前肠道准备中的清洁和祛泡效果。方法将行胶囊内镜检查的278例患者随机分成研究组和对照组,均使用聚乙二醇电解质散2袋口服进行肠道准备,研究组于检查前1 h服用西甲硅油乳剂30m L。观察两组患者肠道准备清洁度、肠道气泡量、不良反应发生情况、胶囊内镜小肠通过时间、全小肠检查成功率等指标。结果研究组肠道气泡量明显少于对照组(P<0.01),肠道准备过程中的不良反应发生率明显低于对照组(P<0.01)。两组患者肠道准备清洁度、胶囊内镜检查中的不良反应发生率、胶囊内镜小肠通过时间及全小肠检查成功率比较差异无统计学意义(P>0.05)。结论西甲硅油能够有效地去除胶囊内镜检查前肠道准备过程中产生的气泡,提高胶囊内镜检查时肠道视野清晰度,且能减少患者肠道准备过程中不良反应的发生。
Objective To observe the effect of simethicone in cleaning and eliminating the bubble in the intestine preparation before capsule endoscopy. Methods 278 patients undergoing capsule endoscopy were randomly divided into study group and control group. All rabbits were given 2 bags of oral polyethylene glycol (PEG) electrolyte for oral preparation. The study group received 30 mL of simethicone emulsion 1 h before the test. The intestine preparation cleanliness, intestinal bubble volume, incidence of adverse reactions, capsule endoscopic transit time, and the success rate of small intestine examination were observed in two groups of patients. Results The number of intestinal bubbles in the study group was significantly less than that in the control group (P <0.01). The incidence of adverse reactions during the intestinal preparation was significantly lower than that in the control group (P <0.01). There was no significant difference in the intestinal preparation cleanliness, incidence of adverse reactions in capsule endoscopy, capsule endoscopy passage time and total small intestine examination in both groups (P> 0.05). Conclusion Simethicone can effectively remove air bubbles during the process of intestinal preparation before capsule endoscopy, improve the clarity of intestinal vision during capsule endoscopy, and reduce the incidence of adverse reactions during intestinal preparation.