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目的:观察加味六君子汤联合化疗治疗中晚期胃癌的疗效。方法:单一化疗对照组和加味六君子汤治疗组,观察2组患者治疗前后临床证候、血清CA19-9及CEA、T淋巴细胞及亚群、生活质量等相应指标的变化。结果:临床证候表现:治疗组总有效率88.21%,对照组57.89%,两组之间比较有差异(P<0.05);两组血清CA19-9、CEA水平变化:治疗前两组之间具有可比性(P<0.05),经治疗后两组比较有差异(P<0.0);两组T淋巴细胞及亚群水平比较:两组治疗前CD4/CD8值无差异性(P<0.05),具有可比性。
Objective: To observe the effect of Modified Liujunzi Decoction combined with chemotherapy on advanced gastric cancer. Methods: The single chemotherapy control group and Jiawei Liujunzi Decoction group were used to observe the changes of clinical syndromes, serum CA19-9, CEA, T lymphocytes and subgroups and the quality of life before and after treatment. Results: The clinical syndromes showed that the total effective rate was 88.21% in the treatment group and 57.89% in the control group, with significant difference between the two groups (P <0.05). The changes of serum CA19-9 and CEA level in the two groups were (P <0.05). There was significant difference between the two groups after treatment (P <0.0). The levels of T lymphocytes and subgroups in the two groups were not significantly different before treatment (P <0.05) , Comparable.