应用PCR及Elisa技术对32例拟诊为先天性感染的新生儿进行了研究,确诊为HCMV感染 11例,诊断阳性率为 34.4％。提出早期诊断的关键在于对可能发生宫内感染的各种因素进行分析筛查,如孕期明确感染史、新生儿临床表现为非特异性多系统损害者。生后3天内血清IgM含量升高提示先天性感染,进一步做实验检查、早确诊、早治疗,以减少多系统损害及中枢神经系统后遗症。 A total of 32 newborns diagnosed as congenital infection were studied by PCR and Elisa techniques. Of the 11 cases diagnosed as HCMV infection, the positive rate was 34.4%. The key to early diagnosis lies in the analysis and screening of various factors that may occur intrauterine infection, such as a clear history of infection during pregnancy, neonatal clinical manifestations of non-specific multi-system damage. Increased serum IgM within 3 days after birth suggests a congenital infection and further tests, early diagnosis and early treatment to reduce multiple system damage and central nervous system sequelae.