直肠良性孤立性溃疡又称“直肠良性非特异性溃疡”、“直肠良性溃疡综合征”、“深部扩张性囊性结肠炎”。本病很少见,1830年Cruveilhier首先报告,但直到本世纪60年代始由Madigan和Morson等肯定。迄今有文献记录的约110例(国内5例)。鉴于国内报告甚少,就此病的一些方面综述如下,以引起同行的注意。病因与发病原理病因与发病原理尚未明确。Haskell等探讨了有关血管、神经、内分泌、创伤及感染方面的因素,但未找到引起溃疡的原因。Schweiger和Duff强调与直肠脱垂有关。Kennedy等报告45例直肠溃疡,其中22例有直肠 Rectal benign solitary ulcers, also known as “benign non-specific rectal ulcer”, “benign ulcer syndrome,” “deep distending cystic colitis.” The disease is rare, with Cruveilhier first reporting in 1830 but not until the 1960s by Madigan and Morson et al. So far there are about 110 documented cases (5 cases in China). Given the small number of domestic reports, some aspects of the disease are summarized below to attract the attention of peers. Etiology and pathogenesis The etiology and pathogenesis have not yet been clarified. Haskell et al explored factors related to blood vessels, nerves, endocrine, trauma and infection, but did not find the cause of ulcers. Schweiger and Duff emphasize rectal prolapse. Kennedy et al reported 45 cases of rectal ulcer, of which 22 cases had a rectum