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目的探讨定量组织速度成像(QTVI)技术与冠状动脉狭窄左室相关的节段心肌运动速度变化的定量关系。方法应用定量组织速度成像技术对31例冠状动脉造影证实的冠状动脉狭窄病人(病变组)和21例正常人(对照组)左室心肌的12个节段测量其QTVI曲线的收缩期峰值速度(Vs)、舒张早期峰值速度(Ve)和舒张晚期峰值速度(Va)。结果左前降支、回旋支和右冠状动脉狭窄供血区节段心肌的Vs、Ve与正常组比较均具有显著性差异(P<0.001或P<0.05),Va则无统计学意义。左前降支狭窄轻、中、重度狭窄组之间各指标相比均无显著性差异。结论定量组织速度成像的Vs和Ve能较准确地检出冠心病人静息状态下冠状动脉狭窄供血区的异常心肌节段,但对区分冠状动脉的狭窄程度似无显著作用。
Objective To investigate the quantitative relationship between quantitative tissue velocity imaging (QTVI) and left ventricular related segment myocardial velocity in patients with coronary artery stenosis. Methods Quantitative tissue velocity imaging was used to measure the peak systolic velocity of QTVI curve in 31 patients with coronary artery stenosis confirmed by coronary angiography (lesion group) and 12 normal subjects (control group) Vs), early diastolic velocity (Ve) and late diastolic velocity (Va). Results Vs, Ve of segmental myocardium in the left anterior descending branch, the circumflex branch and right coronary artery were significantly different from those in the normal group (P <0.001 or P <0.05), while Va was not statistically significant. There was no significant difference in each index between the left anterior descending branch stenosis, moderate to severe stenosis group. Conclusion Quantitative tissue velocity imaging of Vs and Ve can be more accurately detected coronary artery stenosis coronary artery stenosis in the supply of abnormal myocardial segments, but there is no significant difference between the severity of coronary stenosis.