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目的 探讨复方丹参注射液治疗新生儿缺氧缺血性脑病 (HIE)的疗效。方法 将 112例HIE患儿随机分成治疗组及对照组 ,治疗组在原有对症支持治疗及应用胞二磷胆碱基础上加用复方丹参注射液。所有病例均采用新生儿行为神经测定法 (NBNA)于生后 12～ 14d接受NBNA评估。结果 治疗组预后正常为 5 4例 ,预后不良为 2例 ,对照组预后正常为 40例 ,预后不良为 16例 ,两组比较差异有显著性 (P <0 0 5 ) ,治疗组疗效明显优于对照组。结论 复方丹参注射液治疗HIE疗效确切 ,值得推广。
Objective To investigate the curative effect of Fufang Danshen injection on neonatal hypoxic-ischemic encephalopathy (HIE). Methods One hundred and twelve children with HIE were randomly divided into treatment group and control group. The treatment group was given compound Danshen injection on the basis of symptomatic supportive therapy and citicoline. Neonates Behavioral Nerve Test (NBNA) was performed in all cases to assess NBNA at 12-14 days after birth. Results The prognosis of the treatment group was 54 cases, with a poor prognosis of 2 cases. The control group had a normal prognosis of 40 cases and a poor prognosis of 16 cases. There was significant difference between the two groups (P <0.05) In the control group. Conclusion Compound Danshen injection for the treatment of HIE exact effect, it is worth promoting.