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急性淋巴细胞性白血病(ALL)是B细胞或T细胞分化中的一种克隆性增殖。这些细胞保留着淋巴细胞分化前的相应特征。特异性单克隆抗体的产生,对ALL细胞分化程度提供了有效的识别途径。ALL患者中有15～25％白血病细胞表现有骨髓抗原和淋巴抗原,骨髓抗原表现(MAE)与ALL其它特征及预后的关系一直有争论。 1985年1月～1989年12月,洛杉矶儿童医院诊断ALL236例,其中<1岁6例,1～9岁184例,1_0～18岁46例;男134例,女102例。全部病人进行
Acute lymphoblastic leukemia (ALL) is a clonogenic proliferation of B cell or T cell differentiation. These cells retain the corresponding features before lymphocyte differentiation. The production of specific monoclonal antibodies provides an effective means of recognizing the degree of ALL cell differentiation. It has been debated whether 15 to 25% of leukemic cells in ALL patients exhibit bone marrow antigens and lymphoid antigens, and the relationship between bone marrow antigen (MAE) and other characteristics and prognosis of ALL. January 1985 ~ December 1989, Los Angeles Children’s Hospital diagnosis of ALL236 cases, of which <1 year in 6 cases, 184 cases of 1 to 9 years old, 46 cases of 1_0 to 18 years; 134 males and 102 females. All patients