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目的:探讨过敏性紫癜性肾炎的临床、病理特点。方法:对60例过敏性紫癜性肾炎患者的临床及病理资料进行回顾分析。结果:2/3患者无明确诱因,隐匿性肾炎及肾病综合征为其主要临床表现,病理类型以轻度系膜增生型多见,1/3患者伴有新月体形成,近半数患者伴有间质小管损害,免疫荧光以IgA沉积为主。结论:紫癜性肾炎在成人中并不少见,且临床表现多种多样,病理改变轻重不一,对曾患过敏性紫癜的患者应加强监测,密切随访。
Objective: To investigate the clinical and pathological features of allergic purpura nephritis. Methods: The clinical and pathological data of 60 patients with Henoch-Schonlein purpura nephritis were retrospectively analyzed. Results: Two thirds of patients had no definite cause. Occult nephritis and nephrotic syndrome were the main clinical manifestations. Mild mesangial hyperplasia was the most common pathological type. One third of patients had crescent formation, and nearly half of patients had complication There are interstitial tubule damage, immunofluorescence to IgA deposition. Conclusion: Purpura nephritis is not uncommon in adults, and its clinical manifestations are varied. Pathological changes vary in severity. Patients with previously acquired allergic purpura should be monitored intensively and closely followed up.