论文部分内容阅读
蓝氏贾第鞭毛虫病呈全球性分布,在发达国家和发展中国家均有感染,威胁着人类的健康和生命。目前治疗蓝氏贾第鞭毛虫病的药物主要是硝基咪唑类,如甲硝唑,随着长时间的临床应用,耐药虫株不断出现,但是新药的研究周期很长。近年来,如何更好地开发现有药物的新药理作用和研发新药,成为研究蓝氏贾第鞭毛虫病治疗的热点之一。本文就这些药物及其新近研究进展作一综述。
Giardia lamblia disease is a global distribution, both in developed and developing countries are infected, threatening human health and life. The current treatment of Giardia lamblia drugs are mainly nitroimidazoles, such as metronidazole, with the prolonged clinical application, drug-resistant strains appear constantly, but the new drug research cycle is very long. In recent years, how to better develop the new pharmacological effects of existing drugs and develop new drugs become one of the hot spots for the study of the treatment of Giardia lamblia. This article reviews the progress of these drugs and their recent research.