近年来,对乙型肝炎病毒(HBV)基因上前S_2区及其所编码的蛋白(前S_2蛋白)的研究已成为HBV的新课题。认为它与HBV的感染和复制有密切关系。为进一步分析前S_2蛋白与HBV血清学标志的关系,我们采用酶联法检测了83例(166例次)各型乙型肝炎活动期和恢复期血清前S_2蛋白水平,同时与血清HBsAg、HBeAg、PHSA、HBV-DNA及ALT进行了比较,现将实验结果报告如下。 In recent years, the research on the former S 2 region of HBV gene and its encoded protein (pre S 2 protein) has become a new topic of HBV. Think it is closely related to HBV infection and replication. In order to further analyze the relationship between pre-S 2 protein and HBV serological markers, we detected the levels of pre-S 2 protein in 83 cases (166 cases) of hepatitis B during active and convalescent phase by enzyme-linked immunosorbent assay (ELISA) , PHSA, HBV-DNA and ALT were compared, the experimental results are reported as follows.