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用高效液相色谱法以家兔为实验对象,对国产替沃噻吨胶囊与进口片剂各自进行了绝对生物利用度比较及动力学研究,并按两室模型一级消除动力学计算出两种剂型的各种参数。结果表明,国产胶囊的生物利用度可与进口片剂相媲美。
Using high performance liquid chromatography (HPLC) in rabbits as experimental subjects, the absolute bioavailability and kinetics of domestic Wotithetan capsules and imported tablets were studied respectively and the two-compartment model A variety of formulations of the parameters. The results show that the bioavailability of domestic capsules comparable with imported tablets.