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本文对糖基化血红蛋白(GHb)与血浆蛋白(GPP)比色法测定的方法学作了研究,测定了正常人49例与糖尿病病人68例的GHb与GPP浓度,结果显示正常人与糖尿病病人之间有非常显著性差异,糖尿病病人中平均GHb与GPP浓度及二者与平均血糖浓度之间有显著的相关性,证明GHb与GPP均为糖尿病控制较准确的客观指标。本文中24例并有微血管病变与12例未并发微血管病变的糖尿病病人平均GPP与GHb浓度有显著性差异,表明蛋白质糖基化作用对糖尿病性微血管病变的发生发展有一定的联系。
In this paper, glycated hemoglobin (GHb) and plasma protein (GPP) method for the determination of colorimetric method was studied in 49 cases of normal subjects and diabetic patients with GHb and GPP concentrations of 68 cases, the results showed that normal and diabetic patients There was a significant difference between the average of GHb and GPP in patients with diabetes and the two were significantly correlated with the average blood glucose concentration, GHb and GPP are more accurate indicators of the objective of diabetes control. The average GPP and GHb concentrations of 24 diabetic patients with microangiopathy and 12 non-concurrent microangiopathy were significantly different in this paper, indicating that protein glycosylation has a certain relationship with the development of diabetic microangiopathy.