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大血藤来源于木通科植物大血藤Sargentodoxa cuneata的干燥藤茎。该研究通过HPD-100大孔树脂、反复硅胶柱色谱、Sephadex LH-20和制备液相等方法,从采自安徽黄山的大血藤藤茎中分离出20个化合物;根据化合物的理化性质和波谱数据,分别鉴定为(7R,8S)-3,3’-5-三甲氧基-4,9-二羟基-4’,7-环氧-5’,8-木脂素-7’-烯-9’-酸4-O-β-D-吡喃葡萄糖苷(1),1-O-香草酸-6-O-香草酰基吡喃葡萄糖苷(2),对羟基苯乙醇-6-O-香豆酰吡喃葡萄糖苷(3),枸橼苦素B(4),桂皮苷(5),(-)-异落叶松脂素4’-O-β-D-吡喃葡萄糖苷(6),(-)-异落叶松脂素4-O-β-D-吡喃葡萄糖苷(7),1-O-香草酸-6-(3″,5″-二甲氧基-没食子酰)-β-D-吡喃葡萄糖苷(8),对羟基苯乙醇-6-O-(E)-咖啡酰吡喃葡萄糖苷(9),(-)-丁香树脂醇4’-O-β-D-吡喃葡萄糖苷(10),(-)-丁香树脂醇双葡萄糖苷(11),野菰苷(12),木通苯乙醇苷B(13),4-羟基-3-甲氧基苯乙酮-4-O-α-L-鼠李糖-(1→6)-β-D-吡喃葡萄糖苷(14),4-羟基-3-甲氧基苯乙酮-4-O-β-D-芹糖-(1→6)-β-D-吡喃葡萄糖苷(15),(-)-表儿茶素(16),毛柳苷(17),3,4-二羟基苯乙醇吡喃葡萄糖苷(18),绿原酸(19),原儿茶酸(20),其中化合物1为新化合物,化合物2～7首次从该植物中分离得到。
Sapodilla originates from the dry cane of the genus Sargentodoxa cuneata. In this study, 20 compounds were isolated from Cynanchum komarovii cane collected from Huangshan, Anhui by HPD-100 macroporous resin, repeated silica gel column chromatography, Sephadex LH-20 and preparative liquid phase method. According to the physicochemical properties and The spectral data were identified as (7R, 8S) -3,3’-5-trimethoxy-4,9-dihydroxy-4 ’, 7-epoxy-5’, 8-ligno- 4-O-β-D-glucopyranoside (1), 1 -O-vanilloid-6-O-vanillyl glucopyranoside (2), p- (4), Cinnamyl glucoside (5), (-) - Isolongluk pinin 4’-O-β-D-glucopyranoside ( 6), (-) - lammitin 4-O-β-D-glucopyranoside (7), 1 -O- vanillic acid 6- (3 “, 5” -dimethoxy-galloyl ) -β-D-glucopyranoside (8), p-hydroxyphenylethanol-6-O- (E) -cafrogoglucopyranoside (9) (10), (-) - syringalginobioside (11), glycosides (12), woodpridinoside B (13), 4-hydroxy- (1 → 6) -β-D-glucopyranoside (14), 4-hydroxy-3-methoxyacetophenone 4- O-β-D-cystatin- (1 → 6) -β-D-pyridine Glucoside (15), (-) - epicatechin (16), vitorin (17), 3,4- dihydroxyphenethyl alcohol glucopyranoside (18), chlorogenic acid (19) Theophylline (20), in which compound 1 is a new compound, compounds 2 to 7 were isolated from this plant for the first time.