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目的:探讨神经节苷脂治疗新生儿缺氧缺血性脑病的临床疗效。方法:选取确诊的缺氧缺血性脑损伤患儿200例,将其随机分为对照组和观察组,对对照组患儿进行常规的治疗,对观察组在此基础上应用神经节苷脂;结果:经治疗后,观察组患儿的原始反射、张力恢复时间、住院时间等方面均要优于对照组,差异具有统计学意义(P<0.01)。结论:神经节苷脂GM1治疗新生儿缺氧缺血性脑损伤具有较好的临床疗效,可实现进一步的推广应用。
Objective: To investigate the clinical efficacy of ganglioside in the treatment of neonatal hypoxic-ischemic encephalopathy. Methods: 200 cases of children with hypoxic-ischemic brain damage were selected and randomly divided into control group and observation group. Children in control group were treated routinely. Based on the observation group, ganglioside Results: After treatment, the original reflex, tension recovery time and hospital stay of the observation group were superior to the control group, the difference was statistically significant (P <0.01). Conclusion: Ganglioside GM1 has good clinical curative effect in neonatal hypoxic-ischemic brain injury and can be further popularized and applied.