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为观察30%Intralipid与20%Intralipid两种脂肪乳剂对血脂代谢的影响,本文以40例外科非应激与无代谢异常病人为对象,随机分为30%组与20%组,分别经外周静脉予等热量的30%Intralipid及20%In-tralipid,连续使用3d。于实验前后检测外周静脉血甘油三酯,总胆固醇,异常脂蛋白及载脂蛋白的变化。结果显示:两组研究前后血甘油三酯水平均无明显变化。20%组血胆固醇,异常脂蛋白及载脂蛋白B水平于输注后显著升高,而30%组则略有下降。作者认为,决定脂肪乳剂影响血脂代谢的因素并不是其甘油三酯含量而是其磷脂/甘油三酯含量比。选择具有较低磷脂/甘油三酯比的脂肪乳剂对减少高脂血症的发生有重要意义。
In order to observe the effects of 30% Intralipid and 20% Intralipid lipid emulsions on lipid metabolism, 40 patients with non-stress and non-metabolic abnormalities were randomly divided into 30% and 20% To equal heat 30% Intralipid and 20% In-tralipid, continuous use 3d. Peripheral venous blood triglyceride, total cholesterol, abnormal lipoprotein and apolipoprotein were detected before and after the experiment. The results showed that there was no significant change in triglyceride levels between the two groups before and after the study. 20% of the group of blood cholesterol, abnormal lipoprotein and apolipoprotein B levels increased significantly after infusion, while the 30% group was slightly decreased. The author believes that the factors that determine fat emulsion affect blood lipid metabolism is not its triglyceride content but its phospholipid / triglyceride content ratio. Choosing a lipid emulsion with a lower phospholipid / triglyceride ratio is important for reducing the incidence of hyperlipidemia.