细粒棘球蚴病(Echinococcosis)的化学治疗是近十多年来兴起的热门研究课题。苯并咪唑类化合物(Benzimidazoles)被认为具有较好的抗包虫药理活性。但大多数研究是在实验室人 感染细粒棘球蚴的小鼠体内进行的,距实际应用还有一定的距离。作者等用国产阿苯达唑对绵羊体内原发性细粒棘球蚴进行了治疗试验,并用扫描电镜观察虫体超微结构的变化。 Chemotherapy for Echinococcosis is a hot topic of research in recent ten years. Benzimidazoles are considered to have good anti-hydatid cyst activity. However, most of the studies were carried out in laboratory mice infected with Echinococcus granulosus, with a certain distance from the actual application. The authors used domestic albendazole treatment of sheep’s primary Echinococcus granulosus, and observed by scanning electron microscopy ultrastructural changes.