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本文是作者在本刊上一期发表题为临床药物评价的意义与方法一文的补充，从以下几个方面阐述了提高上市药物评价有效性问题：四分结果模式；药疗中同一疾病不同严重程度的区别对待；平稳的血药浓度与治疗效应的必要；查明发病机理是治疗学的基石在观地评价综合再分析的结果；在医疗工作中推广非药物疗法。在说明上述问题中，重点引用了1995年美国钙桔抗剂降压治疗评价的教训以及小剂量阿斯匹林用于动脉硬化患者抗血小板疗法的潜在风险。作者强调辩证思维是上市药物评价的指导原则。
This article is the author in this issue of a period entitled clinical evaluation of the meaning of the article and method of supplement, from the following aspects to improve the effectiveness of marketed drugs evaluation question: four-point results of the same disease in the treatment of different serious The level of treatment; steady blood concentration and the need for treatment effect; identify the pathogenesis of the cornerstone of therapeutics in the evaluation of the results of comprehensive reanalysis; in the medical work to promote non-drug therapy. In elucidating the above issues, we highlight the lessons learned from the 1995 evaluation of calcium-depressant antihypertensive therapy in the United States and the potential risks of low-dose aspirin in antiplatelet therapy in patients with atherosclerosis. The authors emphasize that dialectical thinking is the guiding principle for the evaluation of marketed drugs.