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目的 :探讨降糖胰生胶囊 (人参、黄芪、黄连、水蛭等中药组成 )治疗糖尿病的药理作用。方法 :降糖胰生胶囊对实验性糖尿病模型大鼠血糖的影响 ,对实验性糖尿病模型大鼠糖耐量与胰岛素释放的影响 ,对实验性糖尿病模型大鼠胰高血糖素释放的影响 ,对实验性糖尿病模型大鼠肝糖原的影响 ,对肾上腺素性小鼠高血糖的影响。结果 :实验表明 ,降糖胰生胶囊对链脲霉素所致的实验性糖尿病大鼠有明显降低血糖的作用 ,能改善糖耐量和提高血清胰岛素含量 ,同时能降低血浆胰高血糖素的含量 ,并能调节实验性糖尿病大鼠某些血糖代谢环节 ,如促进肝糖原、肌糖原的合成等并能明显降低肾上腺素引起的小鼠血糖升高
Objective: To investigate the pharmacological effects of Jiangtang Yisheng Capsule (Ginseng, Huangqi, Huanglian, Shuizhe, etc.) in the treatment of diabetes. Methods: Effect of Jiangtang Yisheng Capsule on blood glucose of experimental diabetic rats, effect of glucose tolerance and insulin release in experimental diabetic rats, and effect of glucagon release in experimental diabetic rats Effects of Hepatic Glycogen in Rats with Diabetes Mellitus and Hyperglycemia in Adrenergic Mice Results: The experiment showed that Jiangtangyingsheng capsule can significantly reduce blood glucose in experimental diabetic rats caused by streptozotocin, can improve glucose tolerance and increase serum insulin content, and can reduce plasma glucagon content , And can regulate some of the blood glucose metabolism in experimental diabetic rats, such as promoting liver glycogen, muscle glycogen synthesis, etc., and can significantly reduce adrenaline-induced elevated blood glucose in mice