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目的探讨子宫内膜癌术后盆腔淋巴囊肿形成的危险因素。方法收集2009年1月至2016年4月天津医科大学总医院妇产科行盆腔和(或)腹主动脉旁淋巴结切除的子宫内膜癌患者397例,术后发生淋巴囊肿者76例。结果子宫内膜癌盆腔和(或)腹主动脉旁淋巴结切除后淋巴囊肿的发生率为19.14%,单因素分析发现淋巴结切除范围、FIGO分期、术后化疗、术后放疗及术后放疗联合化疗与淋巴囊肿发生相关(P=0.002,P=0.010,P=0.046,P=0.040,P=0.030)。多因素Logistic回归分析,发现盆腔+腹主动脉旁淋巴结切除是淋巴囊肿形成的独立危险因素(P=0.014)。结论淋巴囊肿是子宫内膜癌盆腔和(或)腹主动脉旁淋巴结切除后的常见并发症,采取个体化治疗,避免不必要的大范围的淋巴结清扫,将会减少淋巴囊肿的发生。
Objective To investigate the risk factors of pelvic lymphatic cyst formation after endometrial carcinoma surgery. Methods From January 2009 to April 2016, 397 cases of endometrial cancer who underwent pelvic and / or para-aortic lymph node dissection in the obstetrics and gynecology department of Tianjin Medical University General Hospital were collected. 76 patients had lymphatic cysts after operation. Results The incidence of lymphatic cyst after pelvic and / or para-aortic lymph node resection was 19.14%. The range of lymph node resection, FIGO stage, postoperative chemotherapy, postoperative radiotherapy and postoperative radiotherapy plus chemotherapy were found by univariate analysis It was associated with lymphocyst formation (P = 0.002, P = 0.010, P = 0.046, P = 0.040, P = 0.030). Multivariate Logistic regression analysis showed that pelvic and para-aortic lymph node dissection was an independent risk factor for lymphatic cyst formation (P = 0.014). Conclusion Lymphatic cyst is a common complication after resection of pelvic and / or para-aortic lymph nodes in endometrial cancer. Individualized treatment of lymphatic cyst and avoiding unnecessary lymph node dissection will reduce lymphatic cyst.