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目的探讨小剂量氨茶碱持续静脉滴注在治疗毛细支气管炎中的疗效。方法选择毛细支气管炎患儿190例,随机分为两组,对照组:布地奈德和沙丁胺醇雾化吸入组(95例);氨茶碱治疗组:布地奈德和沙丁胺醇雾化吸入联合小剂量氨茶碱间断静脉泵入治疗组(95例),观察72 h临床疗效。结果两组毛细支气管炎患儿临床症状均有所缓解,以布地奈德、沙丁胺醇雾化吸入联合小剂量氨茶碱间断静脉泵入治疗组临床有效率最高(96.84%),且布地奈德、沙丁胺醇吸入量明显减少。结论小剂量氨茶碱间断静脉泵入联合布地奈德、沙丁胺醇治疗毛细支气管炎疗效确切,并可减少后二者的用药量,未发现不良反应。
Objective To investigate the efficacy of continuous intravenous infusion of low-dose aminophylline in the treatment of bronchiolitis. Methods Ninety children with bronchiolitis were randomly divided into two groups: control group: budesonide and albuterol inhalation group (95 cases); aminophylline group: budesonide and salbutamol inhalation combined with low dose Aminophylline intermittent venous pump into the treatment group (95 cases), observed 72 h clinical efficacy. Results The clinical symptoms of children with bronchiolitis were relieved in both groups. The best effective rate was budesonide, salbutamol inhalation combined with low dose aminophylline intermittent intravenous infusion (96.84%), and budesonide, Salbutamol inhalation decreased significantly. Conclusion Small doses of aminophylline intermittent intravenous infusion of budesonide, salbutamol treatment of bronchiolitis curative effect is exact, and can reduce the dosage of the latter two, no adverse reactions were found.