新月体形成是快速进展型肾小球肾炎的特征之一［１］，常为预后不良的标志。肾功能损害越重、病情进展愈迅速者，肾小球新月体形成的比例也越高。目前对这类患者的治疗虽然有了比较统一的认识，即需要积极、强有力的免疫抑制治疗，但仍迫切需要新的治疗手段以降低终末期肾... Crescent body formation is one of the characteristics of rapidly progressive glomerulonephritis [1], often a sign of poor prognosis. The heavier renal dysfunction, the more rapid progression of the disease, the glomerular crescent formation rate is higher. Although the current treatment of such patients have a more uniform understanding that requires active and powerful immunosuppressive therapy, but still urgently need new treatment to reduce end-stage renal ...