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检测了４２例急性脑梗塞患者血浆与脑脊液（ＣＳＦ）肿瘤坏死因子（ＴＮＦ）水平。结果发现：脑梗塞急性期患者血浆与ＣＳＦＴＮＦ含量显著高于对照组，ＴＮＦ水平与梗塞灶的大小明显相关。提示ＴＮＦ参与了急性脑缺血的炎性反应过程，抑制炎性反应的治疗可能具有潜在的临床价值。
Plasma and CSF levels of tumor necrosis factor (TNF) were measured in 42 patients with acute cerebral infarction. The results showed that the levels of plasma and CSFTNF in patients with acute cerebral infarction were significantly higher than those in the control group, and the level of TNF was significantly correlated with the size of the infarct. It is suggested that TNF participates in the process of inflammatory reaction of acute cerebral ischemia and inhibiting the treatment of inflammatory reaction may have potential clinical value.