胰岛素是一种蛋白质激素,其基本单位是由一条带有一个含-S-S-键小环的肽链 A经二个-S-S-键和另一条肽链 B 连接而成,并具有一定构象。早在这两条肽链的氨基酸排列次序以及三个-S-S-键的位置尚未弄清楚以前,许多科学工作者曾企图用氧化方法使因还原而完全失活的胰岛素重行恢复活力,但都未成功。自从胰岛素的壹级结构阐明后,并没有人很快地去尝试胰岛素的合成,而是在含有两个半胱氨酸基的肽氧化成环规律以及新的 S-保护基的探索方面做了 Insulin is a protein hormone whose basic unit consists of a peptide chain A with a -S-S-bond containing minicircle linked by two -S-S- bonds to another peptide chain B and has a certain conformation. As early as the sequence of amino acid alignment of these two peptide chains and the location of the three -SS- bonds have not yet been clarified, many scientists previously attempted to reactivate the insulin that is completely inactivated by the reduction by oxidation success. Since elucidation of the one-level structure of insulin, no one has been quick to try insulin synthesis, but rather has been done in the exploration of the ring-law and new S-protecting groups of peptides containing two cysteine ​​groups