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目的了解宜昌市2500例孕晚期妇女肝炎病毒感染情况。方法选取2011年6月-2013年9月宜昌市2500例孕晚期妇女作为研究对象,采用酶联免疫吸附试验(ELISA)法检测甲型肝炎病毒(HAV)、乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)、戊型肝炎病毒(HEV)血清学标志物,比较分析各年龄段抗体及血清学标志物检测结果。结果所选孕晚期妇女中共检测出HBs Ag阳性185例(7.4%),抗HAV Ig M阳性5例(0.2%),抗HCV阳性8例(0.3%),抗HEV Ig M阳性11例(0.4%),抗HEV Ig G阳性587例(23.5%)。结论孕晚期妇女肝炎病毒感染情况与年龄存在一定的相关性,监测肝炎病毒感染血清标志物有助于准确诊断病毒性肝炎类型,为针对性治疗提供参考。
Objective To understand the hepatitis C virus infection in 2500 pregnant women in Yichang City. Methods A total of 2500 pregnant women in Yichang from June 2011 to September 2013 were enrolled in this study. Enzyme-linked immunosorbent assay (ELISA) was used to detect hepatitis A virus (HAV), hepatitis B virus (HBV), hepatitis C virus Hepatitis C virus (HCV) and Hepatitis E virus (HEV) serological markers, and comparative analysis of antibody and serological markers of all ages. Results In the third trimester of pregnancy, 185 cases (7.4%) were positive for HBs Ag, 5 cases were positive for anti-HAV Ig M (0.2%), 8 cases were positive for anti-HCV (0.3%), 11 cases were positive for anti-HEV Ig M %), Anti-HEV IgG positive 587 cases (23.5%). Conclusions There is a certain correlation between hepatitis B virus infection and age in the third trimester of pregnancy. Monitoring serum markers of hepatitis virus infection may help to accurately diagnose the type of viral hepatitis and provide a reference for targeted treatment.