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[目的]观察扶正解毒汤联合CAG方案治疗急性髓系白血病的疗效。[方法]对19例住院急性髓系白血病患者进行中西医结合治疗,CAG方案,阿糖胞苷,10mg/m2,1次/12h,皮下注射。第1~14d,阿柔比星,20mg/次,第1、3、5、7d,粒细胞集落刺激因子(G-CSF),200μg/m2,1次/d,皮下注射,第0~13d,白细胞数大于20×109/L时停用。中药治疗,扶正解毒汤,以扶助正气、驱邪解毒(,白花蛇舌草、黄芪、生地黄、景天三七各20g,太子参、天冬、麦冬、南沙参、北沙参、当归、白术、藤梨根、半枝莲、青黛、龙葵各10g,党参15g)。1剂/d,水煎100mL,早晚口服。连续治疗14d为1疗程。观测临床症状、不良反应。治疗1疗程,判定疗效。[结果]CR11例,PR3例,NR5例,总有效率73.68%。[结论]中药扶正解毒汤联合CAG方案治疗急性髓系白血病效果显著,值得推广使用。
[Objective] To observe the curative effect of Fuzheng Jiedu Decoction combined with CAG regimen in the treatment of acute myeloid leukemia. [Method] Nineteen patients with in-hospital acute myeloid leukemia were treated with combination of TCM and Western medicine, CAG regimen, cytarabine, 10mg / m2, once / 12h, subcutaneously. The first to the 14th day, abamectin, 20mg / time, 1,3,5,7 d, granulocyte colony stimulating factor (G-CSF), 200μg / m2, , White blood cells greater than 20 × 109 / L disabled. Chinese medicine treatment, righting detoxification soup, to help righteousness, exorcise evil detoxification (Hedyotis diffusa, Radix Rehmanniae, Rehmanniae, Sedum thirty seven each 20g, heterophylla, aspartame, Ophiopogon japonicus, Atractylodes, rattan root, Scutellaria barbata, indigo, Solanum 10g, Codonopsis 15g). 1 dose / d, decoction 100mL, sooner or later oral. Continuous treatment 14d for a course of treatment. Observed clinical symptoms, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Results] The total effective rate was 73.68% in CR11, PR3 and NR5 cases. [Conclusion] The Chinese medicine Fuzheng Jiedu Decoction combined with CAG regimen is effective in treating acute myeloid leukemia and it is worth to be popularized.