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目的观察康艾注射液联合化疗对晚期消化道肿瘤患者生活质量的影响。方法 120例晚期消化道肿瘤患者随机分为治疗组和对照组,治疗组采用康艾注射液联合化疗,对照组采用单纯化疗,观察临床疗效、临床症状、体重、生存质量、毒副反应在治疗前后的变化。结果治疗后治疗组总有效率为53.3%,对照组为31.7%;治疗组外周血白细胞降低Ⅱ度以上的发生率为35.0%,对照组为58.3%;治疗组治疗后体重增加,临床症状减轻,生存质量评分升高,药物毒副反应发生率降低,两组之间比较有统计学差异(P<0.05)。结论康艾注射液联合化疗治疗晚期消化道肿瘤有明显协同作用,能减轻化疗不良反应,改善临床症状,保护造血系统,提高免疫功能,改善患者的生活质量。
Objective To observe the effect of Kangai injection combined with chemotherapy on the quality of life of patients with advanced gastrointestinal cancer. Methods 120 patients with advanced gastrointestinal cancer were randomly divided into treatment group and control group. The treatment group was treated with Kangai injection combined with chemotherapy. The control group was treated with chemotherapy alone. Clinical efficacy, clinical symptoms, weight, quality of life, Before and after the change. Results After treatment, the total effective rate was 53.3% in the treatment group and 31.7% in the control group. The incidence of peripheral leukopenia in the treatment group was 35.0% lower than that in the control group, and 58.3% in the control group. After treatment, the weight gain and clinical symptoms were relieved , The quality of life score increased, the incidence of drug toxicity decreased, there was a statistically significant difference between the two groups (P <0.05). Conclusion Kangai injection combined with chemotherapy for the treatment of advanced gastrointestinal tumors have a significant synergistic effect, can reduce chemotherapy adverse reactions, improve clinical symptoms, protect the hematopoietic system, improve immune function and improve the quality of life of patients.