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背景:成人哮喘症状与室内环境的关系。 目的:研究当前哮喘症状(喘息或呼吸困难发作)和医院内室内环境及湿度的关系。 设计:在冬季对4家老年医院的全体职工(n=87)进行研究。测定室内空气污染物、混凝土地面湿度、落尘过敏原。按年龄、性别、特应质和参加者自己住所的湿度调整后进行多元逻辑回归分析。 结果:据报告当前有哮喘症状者占17％,8％被医生诊断过哮喘。哮喘症状在2座建筑物中更常见(调整OR=8.6;95％CI 1.3-56.7)。在这2座建筑物的室内空气中,可检测到建筑材料聚氯乙烯(PVc)中双(乙-己基)-邻苯二甲酸盐(DEHP)的潮湿相关降解物:2-乙基-1-己烷(2-32μg/m~3)(CAS nr104-76-7)。哮喘症状与混凝土地面上的相对湿度和地面的氨有关。在由人智学协会所建造的一家最新的医院中,湿度水平较低,哮喘症状也少(4％)。在所有4座建筑的尘土中均发现猫(Fel d1)和狗过敏原(can f1)(几何平均数分别为340ng/g和2490ng/g)。在75％的全部样品中发现户尘螨(Der p1,Der f1,or Der m1)(几何平均数130ng/g)。过敏原的量与哮喘症状间无相关性。 结论:哮喘症状可能与建筑物混凝土地面的湿度增高相关,以及建筑材料中增塑剂DEHP潮湿相关碱化降解的一项指标2-乙基-1-己烷有关。而且老年医院可被猫、狗和尘螨过敏原的明显增加所污?
BACKGROUND: Relationship between adult asthma symptoms and the indoor environment. Objective: To study the current asthma symptoms (wheezing or dyspnea episodes) and the hospital indoor environment and humidity. Design: All winter workers in four geriatric hospitals (n = 87) were studied. Determination of indoor air pollutants, concrete ground humidity, dust allergens. Multivariate logistic regression analysis was performed on the basis of age, gender, attributive quality and humidity of participants’ own residence. Results: Currently, 17% of asthmatics are reported and 8% are diagnosed with asthma by their doctors. Asthma symptoms were more common in two buildings (adjusted OR = 8.6; 95% CI 1.3-56.7). Moisture-related degradation products of bis (ethylene-hexyl) -phthalate (DEHP) in building material polyvinyl chloride (PVc) were detected in the indoor air of the two buildings: 2-ethyl- 1-hexane (2-32 μg / m 3) (CAS nr 104-76-7). Asthma symptoms are related to the relative humidity on the concrete floor and ground floor ammonia. In a state-of-the-art hospital built by the Society for Human Intelligence, the humidity level is low and asthma symptoms are few (4%). Cats (Fel d1) and dog allergens (can f1) were found in the dust of all 4 buildings (geometric mean 340 ng / g and 2490 ng / g, respectively). House dust mites (Der p 1, Der f 1, or Der m 1) were found in 75% of all samples (geometric mean 130 ng / g). There was no correlation between the amount of allergens and asthma symptoms. CONCLUSIONS: Asthma symptoms may be related to increased humidity on the concrete floor of buildings and to 2-ethyl-1-hexane, an indicator of moisture-related alkalinization and degradation of plasticizers DEHP in building materials. And elderly hospitals can be cats, dogs and dust mite allergens increased significantly contaminated?