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目的探讨盐酸米诺环素软膏对牙周炎的治疗效果。方法收集长春市宽城区医院2012年11月~2013年11月收治的120例牙周炎患者的临床资料,将患者随机分为治疗组和对照组,每组60例。对照组采用牙周炎基础治疗,治疗组采用牙周炎基础治疗联合盐酸米诺环素软膏治疗。观察期均为1个月,采用χ2检验对比2组患者疗效。结果治疗组治愈23例,有效32例,无效5例,总有效率为91.67%,对照组分别为10、27、23例,总有效率为61.67%,2组患者疗效差异有统计学意义(P<0.05)。结论基础治疗加盐酸米诺环素软膏可有效控制牙周炎的发展,促进牙周组织细胞再生、减小牙周袋深度,具有理想的临床治疗效果。
Objective To investigate the effect of minocycline hydrochloride ointment on periodontitis. Methods The clinical data of 120 patients with periodontitis admitted from November 2012 to November 2013 in Kuancheng District Hospital of Changchun were collected. The patients were randomly divided into treatment group and control group, with 60 cases in each group. The control group was treated with periodontitis. The treatment group was treated with basic periodontitis combined with minocycline hydrochloride ointment. Observation period were 1 month, using χ2 test compared the efficacy of two groups of patients. Results In the treatment group, 23 cases were cured, 32 cases were effective and 5 cases were ineffective. The total effective rate was 91.67%, while the control group was 10, 27 and 23 cases respectively, with a total effective rate of 61.67%. The difference between the two groups was statistically significant P <0.05). Conclusion The basic treatment plus minocycline hydrochloride ointment can effectively control the development of periodontitis, promote the regeneration of periodontal tissues and reduce the depth of periodontal pocket, which has an ideal clinical therapeutic effect.