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通过临床收集36例不典型GH,对其病史、症状、体征进行详细记录及随访,采用PCR检测局部棉拭子HSV Ⅱ-DNA和ELISA法检测血清抗HSV-Ⅱ的IgM确立诊断,同时检测相关病原体排除诊断,包括真菌、衣原体、支原体、梅毒、淋菌、滴虫等。结果:不典型GH主要表现为:1、生殖器部位细小溃疡;2、男性尿道外口炎症(尿道口炎);3、生殖器非特异性红斑;4、龟头丘疹样小结节;5、非特异性阴道炎。PCR检测HSV Ⅱ-DNA阳性23例(64％),ELISA检测血清抗HSV-Ⅱ的IgM阳性36例(100％)
Thirty-six cases of atypical GH were collected clinically, and their medical history, symptoms and signs were recorded and followed up in detail. HSV Ⅱ-DNA was detected by PCR using local cotton swabs and serum IgM was detected by ELISA. Pathogen exclusion diagnosis, including fungi, chlamydia, mycoplasma, syphilis, gonococcus, trichomoniasis and so on. Results: Atypical GH mainly showed as follows: 1, small ulcer in genital area; 2, male urethral orifice inflammation (urethral stomatitis); 3, genital nonspecific erythema; 4, glans papilloid nodules; 5, nonspecific vaginal inflammation. HSV Ⅱ-DNA was detected by PCR in 23 cases (64%), IgM positive in anti-HSV-Ⅱ by ELISA was 36 cases (100%),