目的　探讨阴道镜诊断宫颈人乳头瘤病毒 (HPV)亚临床感染的价值。方法　对 190例患者行阴道镜检查及多点活检。结果　发现 76例HPV亚临床感染 ,其中宫颈糜烂者占 80 % ,合并宫颈上皮内瘤变者 6 1%。阴道镜检查灵敏度 84 .2 % ,特异度 83%。结论　阴道镜具有无创和可重复性的特点 ,在阴道镜指导下活检结合病理检查 ,可提高HPV亚临床感染的诊断率 Objective To investigate the value of colposcopy in the diagnosis of subclinical cervical intraepithelial neoplasia virus (HPV) infection. Methods Totally 190 patients underwent colposcopy and multi-biopsy. The results found that 76 cases of HPV sub-clinical infection, of which 80% of patients with cervical erosion, cervical intraepithelial neoplasia with 61%. Colposcopy sensitivity of 84.2%, specificity of 83%. Conclusion colposcopy with noninvasive and reproducible features under the guidance of colposcopy biopsy combined with pathological examination can improve the diagnostic rate of HPV sub-clinical infection