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目的:探讨B超引导下冷循环微波刀辅助治疗晚期肝癌的临床效果。方法:164例晚期肝癌患者根据入院顺序随机分为研究组与对照组,各82例。两组首先都采用栓塞治疗,研究组在此基础上加用B超引导下冷循环微波刀治疗。结果:研究组完全缓解12例,部分缓解40例,稳定10例,进展20例,总有效率为63.4%(52/82);对照组中完全缓解8例,部分缓解22例,稳定22例,进展30例,总有效率为36.6%(30/82),研究组疗效优于对照组,两组总有效率比较差异有统计学意义(χ2=5.760,P<0.05)。研究组灭活率为97.6%,对照组灭活率为81.7%,差异有统计学意义(χ2=6.852,P<0.05)。所有患者在治疗后当天均出现上腹部疼痛,均未作特殊处理后消失,无1例术后出现胃肠穿孔等严重并发症。结论:B超引导下冷循环微波刀联合栓塞治疗晚期肝癌安全、有效、实用,值得推广应用。
Objective: To investigate the clinical effect of B-guided cold cycle microwave knife adjuvant treatment of advanced liver cancer. Methods: One hundred and sixty-four patients with advanced hepatocellular carcinoma were randomly divided into study group and control group according to the order of admission, with 82 cases each. Both groups embolized the first treatment, the study group on the basis of the use of B-guided cold cycle microwave knife treatment. Results: The study group completely relieved 12 cases, partial remission in 40 cases, stable in 10 cases, progress in 20 cases, the total effective rate was 63.4% (52/82); control group, complete remission in 8 cases, partial remission in 22 cases, stable in 22 cases , 30 cases progressed, the total effective rate was 36.6% (30/82). The curative effect of the study group was better than that of the control group. There was significant difference between the two groups in total effective rate (χ2 = 5.760, P <0.05). The inactivation rate was 97.6% in the study group and 81.7% in the control group, with significant difference (χ2 = 6.852, P <0.05). All patients had upper abdominal pain on the day after treatment, and no special treatment disappeared. None of the patients had serious complications such as gastrointestinal perforation after operation. Conclusion: It is safe, effective and practical to use B-guided microwave-assisted microwave knives and embolization in the treatment of advanced liver cancer. It is worth popularizing and applying.