“1,6-消除反应”首先由作者之一等提出,这类反应是指δ-取代的αβ-不饱和羰基化合物在酸或硷的催化作用下脱去取代基,并形成αβ,γδ-二烯酮(或醛)的反应。由于取代基所在的碳原子与羰基氧原子的相对位置是“1”与“6”,故称为1,6-消除反应。这类反应的机构如下: The “1,6-elimination reaction” was first proposed by one of the authors, and the like. This type of reaction means that the δ-substituted αβ-unsaturated carbonyl compound is substituted with an acid or a base under the action of catalysis and forms αβ, γδ- The reaction of diketene (or aldehyde). Since the relative position of the carbon atom and the carbonyl oxygen atom where the substituent is located is “1” and “6”, it is called a 1,6-elimination reaction. The mechanism for such reactions is as follows: