【摘 要】
：
目的探究黄连解毒汤对阿尔茨默病(AD)斑马鱼认知功能障碍的影响。方法将126 g黄连,84 g黄柏,84 g黄芩,126 g栀子分别放入10,8和8倍量的水,浸泡30 min,然后100℃分别提取2,1.5和1.5 h,将3次提取液粗滤浓缩为308 g·L-1放入冰箱备用。选取200尾斑马鱼于第1~7天在T型缸进行行为学训练,结束后录像并利用行为学记录分析软件smart3.0进行行为学分析,选出合格斑马鱼,为空白组。除空白组斑马鱼不做任何处理外,其余5组于第8~13天暴露在AlCl3
【基金项目】
：
广西壮族自治区自然科学基金(2017GXNSFAA198255,2018GXNSFBA138028),广西脑与认知神经科学重点实验室开放课题(GKLBCN-20180105-03),2019大学生创新创业项目训练计划(201910601038),第四期广西高等学校千名中青年骨干教师培育计划。
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目的探究黄连解毒汤对阿尔茨默病(AD)斑马鱼认知功能障碍的影响。方法将126 g黄连,84 g黄柏,84 g黄芩,126 g栀子分别放入10,8和8倍量的水,浸泡30 min,然后100℃分别提取2,1.5和1.5 h,将3次提取液粗滤浓缩为308 g·L-1放入冰箱备用。选取200尾斑马鱼于第1~7天在T型缸进行行为学训练,结束后录像并利用行为学记录分析软件smart3.0进行行为学分析,选出合格斑马鱼,为空白组。除空白组斑马鱼不做任何处理外,其余5组于第8~13天暴露在AlCl3
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