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近两年对38例胃癌进行术前~(60)钴照射。本文对30例术前照射标本观察,与同期单纯手术40例对照。 1.本组照射有效率56.6％。根据滝沢氏的X分类,X_1:43％,X_2:40％;X_3:16.6％,照射肿瘤量3,000—4,000rad是适宜的。2.本组未分化癌照射效果最佳,低分化腺癌和管状腺癌次之,乳头状腺癌和粘液腺癌无效。3.间质反应即结缔组织增生和浆、淋巴细胞浸润与对照组比较差异显著(p<0.01)。4.浆膜和粘膜层效果显著。5.胃壁粘膜肌层反应均为可复性的,不影响伤口与吻合口愈合。6.淋巴结转移癌照射有效率62.5％,随照射剂量增加而显著。作者认为胃癌术前照射做为综合治疗措施是可取的。
In the past two years, 38 cases of gastric cancer were preoperatively irradiated with cobalt (60). This article observed 30 cases of preoperative irradiation specimens, compared with 40 cases of simple surgery in the same period. 1. This group has an irradiation efficiency of 56.6%. Based on X’s X classification, X_1: 43%, X_2: 40%, X_3: 16.6%, and the radiation dose of 3,000 to 4,000 rad is appropriate. 2. The group had the best radiation effects on undifferentiated carcinoma, followed by poorly differentiated adenocarcinoma and tubular adenocarcinoma, and no effect on papillary adenocarcinoma and mucinous adenocarcinoma. The interstitial reaction, namely connective tissue hyperplasia and plasma and lymphocyte infiltration, was significantly different from the control group (p<0.01). 4. The serosa and mucous membranes have significant effects. 5. The muscularis mucosal response of the gastric mucosa was irreversible and did not affect wound and anastomotic healing. 6. The effective rate of radiation of lymph node metastasis was 62.5%, which was significant with the increase of irradiation dose. The authors believe that preoperative irradiation of gastric cancer as a comprehensive treatment is desirable.