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目的：对ICU中心静脉导管相关性感染的危险因素和护理进行探讨和分析。方法对我院2010年12月-2014年12月ICU病房收治的30例导管感染患者中90例次中心静脉置管患者作为研究对象，对他们的临床特点、危险因素和护理的关系进行研究。结果①股静脉、颈静脉和锁骨下静脉插管的的感染率分别为33.33%、28.57%和18.52%，其中股静脉置管最高，锁骨下静脉最低。②导管留置的时间越长，感染发生率越高。③单腔导管留置感染率为15.87%，低于双腔导管留置的40.74%。结论严格中心静脉置管护理，提高患者机体免疫力，缩短置管时间，加强护士手卫生的管理和穿刺部位消毒，对降低中心静脉置管相关性感染的发生具有非常重要的作用。“,”Objective:To investigate the risk factors and nursing of the central venous catheter related infection in ICU center..Methods:in our hospital from December 2010 to 2014 December ICU were 30 cases of catheter infection patients in 90 cases of central venous device tube patients as the research object,the relationship of their clinical characteristics,risk factors and nursing were studied.Results:the infection rates of femoral vein,jugular vein and clavicle vein were 33.33%,28.57% and 18.52%,respectively,femoral vein catheterization was the highest,and the lowest was the lowest of clavicle vein..The longer the catheter indwelling,the higher the infection rate..The infection rate of single lumen catheter is 15.87%,which is lower than that of double lumen catheter 40.74%.Conclusion:strict central venous set tube care,improve immunity of patients,shorten the time of catheter,strengthen nurse hand hygiene management and disinfection of puncture site,has a very important role in the occurrence of low central venous catheter related infections.