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目的:探讨老年急性脑梗死患者血尿酸水平与颈动脉粥样硬化斑块的相关性。方法:120例患者均为南京鼓楼医院2013年10月至2016年12月收治的老年急性脑梗死病例,所有患者均测定外周血尿酸、血脂水平,并接受超声检查颈动脉斑块。回顾性分析患者的检查结果,按照是否有斑块分为两组,有斑块组38例、无斑块组82例,分析患者血尿酸水平与颈动脉粥样硬化斑块的关系。结果:两组患者肥胖率、低密度脂蛋白胆固醇(LDL-C)、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)比较,差异具有统计学意义(P<0.05);有斑块组患者血尿酸值显著高于无斑块组,高血尿酸发生率高于无斑块组,差异具有统计学意义(P<0.05)。结论:血尿酸水平高低会对老年急性梗死患者发生颈动脉粥样硬化斑块有一定的影响,除此之外还要关注到年龄、肥胖等原因,因此在诊断时应观察患者是否存在年龄大、肥胖和血尿酸水平过高的情况,由此进行对症治疗。
Objective: To investigate the correlation between serum uric acid level and carotid artery atherosclerotic plaque in elderly patients with acute cerebral infarction. Methods: All 120 patients were aged acute cerebral infarction patients who were admitted to Gulou Hospital from October 2013 to December 2016 in our hospital. All patients had peripheral blood uric acid and blood lipid levels and carotid plaques underwent ultrasound examination. Retrospective analysis of the patient’s test results, according to whether there are plaques divided into two groups, 38 cases with plaque group, no plaque group 82 cases, analysis of patients with serum uric acid levels and carotid atherosclerosis plaque relationship. Results: There were significant differences in obesity rate, LDL-C, TC, TG and HDL-C between the two groups P <0.05). The serum uric acid value of patients with plaque group was significantly higher than that of no plaque group, and the incidence of hyperuricemia was higher than that without plaque group (P <0.05). Conclusion: The level of serum uric acid may affect the occurrence of carotid atherosclerotic plaques in elderly patients with acute infarction. In addition, we should pay attention to the reasons such as age and obesity. Therefore, we should observe whether the patients are older , Obesity and blood uric acid levels are too high, thus symptomatic treatment.